Drug Interactions

Generally this drug class does not interact with testosterone, but there is one potential interaction with oestrogen. The drug atorvastatin in particular, may increase the effects of oestrogen. Although the clinical effects of this interaction are not known, it warrants monitoring drug levels in your blood and potential dose adjustments to avoid hormone level fluctuations. It is best to specify which drugs you are on, or wish to take, with your healthcare professional.

Contraceptive implants, intrauterine devices (the coil), and injections that contain progesterone or its derivatives do not interact with testosterone. Combined oral contraceptive pills that contain oestrogens may not be the preferred option for patients on the transmasculine spectrum, due to their potential feminising effects.

Yes it is possible to be on both drugs at the same time, however there exists a potential interaction between sex hormones and insulin. Taking testosterone or oestrogen together with insulin or certain other diabetes medications may interfere with blood glucose control as they can cause low blood sugar, and/or exacerbate pre-existing diabetes. Close monitoring for the development of low or high blood sugar symptoms is recommended if you take hormones together with insulin, particularly in patien...

Some creatine supplements are known to interact with metabolism of hormones. It is best to specify which supplements you are on, or which supplements you wish to take, with your healthcare professional so that they can check for any potential interaction. Transparent sharing of medical information is necessary to ensure that your care is safe at all times. Please make sure to let us know if you are taking any supplements so we can review this for you and make any necessary adjustments.

Some drugs taken to treat depression are known to interact with metabolism of hormones. It is best to specify which drugs you are on, or which drugs you wish to take, with your healthcare professional so that they can check for any potential interaction. Transparent sharing of medical information is necessary to ensure that your care is safe at all times. Please make sure to let us know if there is any medication that has been newly prescribed so we can review this for you and make any necessary...

Some drugs taken to treat anxiety are known to interact with metabolism of hormones. It is best to specify which drugs you are on, or which drugs you wish to take, with your healthcare professional so that they can check for any potential interaction. Transparent sharing of medical information is necessary to ensure that your care is safe at all times. Please make sure to let us know if there is any medication that has been newly prescribed so we can review this for you and make any necessary ad...